Publication

Last Updated on 2013. 4. 20.

Publication

2013

C–H Bond Activation of the Methyl Group of Supporting Ligand in an Osmium(III) Complex upon the Reaction with H2O2: Formation of an Organometallic Osmium(IV) Complex
Hideki Sugimoto,* Kenji Ashikari, and Shinobu Itoh*
Inorg. Chem. 52 (2), 543-545 (2013).

Copper complexes of non-innocent β-diketiminate ligand containing phenol groups
June Takaichi, Kei Ohkubo, Hideki Sugimoto, Motohiro Nakano, Daisuke Usa, Hiroaki Maekawa, Nobutaka Fujieda, Nagatoshi Nishiwaki, Shu Seki, Shunichi Fukuzumi, and Shinobu Itoh*
Dalton Trans. 41 (7), 2438-2444 (2013).

A new series of bis(ene-1,2-dithiolato)tungsten(IV), -(V), -(VI) complexes as reaction centre models of tungsten enzymes: preparation, crystal structures and spectroscopic properties.
Hideki Sugimoto,* Kohei Hatakeda, Kazuo Toyota, Susumu Tatemoto, Minorun Kubo, Takashi Ogura and Shinobu Itoh*
Dalton Trans. 41 (9), 3059-3070 (2013).

Oxo-sulfido- and oxo-selenido-molybdenum(VI) complexes possessing dithiolene ligand related to the active sites of hydroxylases of molybdoenzymes: Low temperature preparation and characterisation Hideki Sugimoto,* Susumu Tatemoto, Kazuo Toyota, Minoru Kubo, and Shinobu Itoh* Chem. Commun. 49 (39), 4358-4360 (2013).

Activation Mechanism of MelB Tyrosinase from Aspergillus oryzae by Acidic Treatment Nobutaka Fujieda,* Michiaki Murata, Shintaro Yabuta, Takuya Ikeda, Chizu Shimokawa, Yukihiro Nakamura, Yoji Hata, Shinobu Itoh* J. Biol. Inorg. Chem. 18 (1), 19-26 (2013).

2012

An Osmium(III)/Osmium(V) Redox Couple Generating OsV(O)(OH) Center for cis-1,2-Dihydroxylation of Alkenes with H2O2: Os Complex with a Nitrogen- based Tetradentate Ligand Hideki Sugimoto,* Kazuhiro Kitayama, Seiji Mori, and Shinobu Itoh* J. Am. Chem. Soc. 134 (46), 19270-19280 (2012).

Active Site Models for the CuB Site of PHM and DβH Atsushi Kunishita, Mehmed Z. Ertem, Yuri Okubo, Tetsuro Tano, Hideki Sugimoto, Kei Ohkubo, Nobutaka Fujieda, Shuichi Fukuzumi, Christopher J. Cramer,* and Shinobu Itoh* Inorg. Chem. 51 (17), 9465-9480 (2012).

Heterolytic Alkylhydroperoxide O–O Bond Cleavage by Copper(I) Complexes Tetsuro Tano, Hideki Sugimoto, Nobutaka Fujieda, and Shinobu Itoh* Eur. J. Inorg. Chem. 2012 (26), 4099–4103 (2012)

Copper(I)-Dioxygen Reactivity in a Sterically Demanding Tripodal Tetradentate tren Ligand. Formation and Reactivity of a Mononuclear Copper(II) End-on Superoxo Complex Yuki Kobayashi, Kei Okubo, Takashi Nomura, Minoru Kubo, Nobutaka Fujieda, Hideki Sugimoto, Shunichi Fukuzumi, Kei Goto, Takashi Ogura, and Shinobu Itoh* Eur. J. Inorg. Chem. 2012 (29), 4574-4578. [Cover Picture]

Artificial Dicopper Oxidase: Rational Reprogramming of Bacterial Metallo-β-lactamase into a Catechol Oxidase Nobutaka Fujieda,*; Atsushi Hasegawa, Kenichi Ishihama, and Shinobu Itoh* Chem. Asian J. 2012, 7 (6), 1203–1207. [Special Issue of 150 years of German–Japanese friendship]

Multifunctions of MelB, a Fungal Tyrosinase from Aspergillus oryzae
Nobutaka Fujieda,* Michiaki Murata, Shintaro Yabuta, Takuya Ikeda, Chizu Shimokawa,
Yukihiro Nakamura, Yoji Hata, and Shinobu Itoh*
ChemBioChem. 13 (2), 193–201 (2012).

2011

Copper-Oxygen Chemistry
Kenneth D. Karlin and Shinobu Itoh, Eds
John Wiley & Sons, Inc., Hoboken, New Jersey, 2011.

Chapter 8. Chemical Reactivity of Copper-Active Oxygen Complexes
Shinobu Itoh

Synthesis and Properties of Oxo-carboxylato- and Dioxo-bridged Diosmium Complexes of Tris(2- pyridylmethyl)amine Hideki Sugimoto,* Kazuhiro Kitayama Kenji Ashikari, Chikako Matsunami, Naomi Ueda, Keisuke Umakoshi, Yuko Hosokoshi, Yoichi Sasaki,* and Shinobu Itoh* Inorg. Chem. (Full Paper), 50 (18), 9014-9023 (2011).

Redox Reaction of Bis(dithiolene)sulfidotungsten(IV) Complex with Elemental Sulfur: Functional Analogues of Polysulfide Reductase of Molybdoenzymes. Hideki Sugimoto,* Reiko Tajima, Kazuo Toyota, Hiroyuki Miyake, and Shinobu Itoh* Chem. Lett. (Letter) 40 (10), 1146-1148 (2011). Editor’s Choice  
Reactivity of copper(II)-alkylperoxo complexes. Tetsuro Tano, Mehmed Z. Ertem, Satoru Yamaguchi, Atsushi Kunishita, Hideki Sugimoto, Nobutaka Fujieda, Takashi Ogura, Christopher J. Cramer,* and Shinobu Itoh*
Dalton Trans. (Full Paper), 40 (40), 10326-10336 (2011). Front Cover & Hot Article

40th Anniversary Issue of Dalton Trans.

Post-translational His-Cys Cross Linkage Formation in Tyrosinase Induced by Copper(II)-Peroxo Species. Nobutaka Fujieda, Takuya Ikeda, Michiaki Murata, Sachiko Yanagisawa, Shigetoshi Aono, Kei Ohkubo, Satoshi Nagao, Takashi Ogura, Shun Hirota, Shunichi Fukuzumi, Yukihiro Nakamura, Yoji Hata, and Shinobu Itoh*
J. Am. Chem. Soc. (Communication), 133 (5), 1180–1183 (2011).

Reactions of Copper(II)-Phenol Systems with O2. Models Reaction for TPQ -Biosynthesis in in Copper Amine Oxidases. Kae Tabuchi, Mehmed Z. Ertem, Hideki Sugimoto, Atsushi Kunishita, Tetsuro Tano, Nobutaka Fujieda, Mehmed Z. Ertem,‡ Christopher J. Cramer,* and Shinobu Itoh* Inorg. Chem. (Article), 50 (5), 1633–1647 (2011).

Generation of bis(dithiolene)dioxomolybdenum(VI) complexes from bis(dithiolene)monooxomolybdenum(IV) complexes by proton-coupled electron transfer in aqueous media Hideki Sugimoto,* Hiroyuki Tano, Hiroyuki Miyake, and Shinobu Itoh* Dalton Trans. (Full Paper), 40 (10), 2358–2365 (2011).

Chalcogenidobis(ene–1,2–dithiolate)molybdenum(IV) complexes (chalcogenide E = S, Se): Probing Mo≡E and ene–1,2–dithiolate substituent effects on geometric and electronic structure. Hideki Sugimoto,* Hiroyuki Tano, Koichiro Suyama, Tomoya, Kobayashi, Hiroyuki Miyake, Shinobu Itoh,* Regina P. Mtei, and Martin L. Kirk* Dalton Trans. (Full Paper), 40 (5), 1119–1131 (2011).

Synthesis and Magnetic Properties of Dimethylmethylenebis(iminonitroxide) Diradical Shuichi Suzuki, Noriaki Itoh, Kimiaki Furuichi, Masatoshi Kozaki, Daisuke Shiomi, Kazunobu Sato, Takeji Takui, Hiromi Ohi, Shinobu Itoh, and Keiji Okada* Chem. Lett. (Communication), 40 (1), 22–24 (2011).

2010

Five monomeric hemocyanin subunits from Portunus trituberculatus: Purification, spectroscopic characterization, and quantitative evaluation of phenol monooxygenase activity. Nobutaka Fujieda, Aki Yakiyama, and Shinobu Itoh* Biochem. Biophys. Acta (Full Paper), 1804, 2128-2135 (2010).
 Resonance Raman Spectra of β-Diketiminato Copper(II) Complexes Tomoko Miyazaki, Chizu Shimokawa, Toshio Matsushita, Shinobu Itoh, Junji Teraoka* Bull. Chem. Soc. Jpn. (Full Paper), 83 (9), 1162-1169 (2010). Selected Paper

Seven-coordinate Rhenium(III) Complexes with a Labile Coordination Site Assembled on Indium-doped Tin-oxide (ITO) Electrodes: Catalytic Reduction of Dioxygen to Hydrogen Peroxide
Hideki Sugimoto,* Hiroyuki Tano, Hiroyuki Miyake, and Shinobu Itoh*
Chem. Lett. (Communication), 39 (9), 986–988 (2010).

Oxygenation Chemistry at Mononuclear Copper(II)-Hydroquinone System with O2
Kae Tabuchi, Hideki Sugimoto, Atsushi Kunishita, Nobutaka Fujieda, and Shinobu Itoh*
Inorg. Chem. (Communication), 49 (15), 6820–6822 (2010).  Monooxo Molybdenum(VI) Complexes Possessing Olefinic Dithiolene Ligands: Probing Mo-S Covalency Contributions to Electron Transfer in DMSO Reductase Family Molybdoenzymes
Hideki Sugimoto,* Susumu Tatemoto, Koichiro Suyama, Hiroyuki Miyake, Regina P. Mtei, Shinobu Itoh,* and Martin L. Kirk*
Inorg. Chem. (Communication), 49 (12), 5368-5370 (2010).

Nickel(II) Complexes of tpa Ligands with 6-Phenyl Substituents (Phntpa). Structure and H2O2-Reactivity
Tetsuro Tano, Yoshitaka Doi, Masayuki Inosako, Atsushi Kunishita, Minoru Kubo, Hirohito Ishimaru, Takashi Ogura, Hideki Sugimoto, and Shinobu Itoh*
Bull. Chem. Soc. Jpn. (Full Paper) 83 (5), 530-538 (2010). Selected Paper

Catalytic oxygenation of phenols by arthropod hemocyanin, an oxygen carrier protein, from Portunus trituberculatus
Nobutaka Fujieda, Aki Yakiyama, and Shinobu Itoh*
Dalton Trans. (Full Paper), 39, 3083-3092 (2010).

Hydrodesulfurization of Bis(dithiolene)oxo(disulfido)tungsten(VI) Complex Related to the Reaction Center of the Fourth Tungsten–Containing Enzyme (WOR4) from Pyrococcus furiosus. Hideki Sugimoto,* Hiroyuki Tano, Kazuo Toyota, Reiko Tajima, Hiroyuki Miyake, Isao Takahashi, Shun Hirota, and Shinobu Itoh* J. Am. Chem. Soc. (Communication), 132 (1), 8–9 (2010).

ブルース有機化学概説（第２版）（化学同人，大船泰史，香月勗，西郷和彦，富岡清　監訳） 伊東　忍 教科書 (18章) (訳) (2010). 
銅タンパク質の水酸化反応触媒としての応用 藤枝伸宇、伊東　忍 化学工業、61 (9), 711-715 (2010).

2009

Dioxo-Molybdenum(VI) Complexes with Ene-1,2-dithiolene Ligands: Synthesis, Spectroscopy, and Oxygen Atom Transfer Reactivity Hideki Sugimoto,* Susumu Tatemoto, Koichiro Suyama, Hiroyuki Miyake, Shinobu Itoh,* Chao Dong, Jing Yang, and Martin L. Kirk* Inorg. Chem. 48 (21), 10150–10157 (2009).

(μ-η2:η2-Disulfido)dinickel(II) complexes supported by 6-methyl-TPA ligands Atsushi Kunisita, Masayuki Inosako, Minoru Kubo, Takashi Ogura, Hideki Sugimoto, and Shinobu Itoh* Dalton Trans. (43) 9410–9417 (2009) (Selected Paper for Cover Picture).

A Stable Cu2O2 Complex Supported by an Asymmetric Dinucleating Pentapyridine Ligand Involving an Amide Linkage Yoshimitsu Tachi, Yumi Matsukawa, Junji Teraoka, and Shinobu Itoh Chem. Lett. 38 (3) 202–203 (2009).

Ni(II)/H2O2 Reactivity in Bis[(pyridin-2-yl)methyl]amine Tridentate Ligand Sysetm. Aromatic Hydroxylation Reaction by Bis(μ-oxo)dinickel(III) Complex Atsushi Kunishita, Yoshitaka Doi, Takashi Ogura, Hideki Sugimoto, and Shinobu Itoh* Inorg. Chem. 48 (11), 4997–5004 (2009).

Mononuclear Copper(II)-Superoxo Complex that Mimics the Structure and Reactivity of the Active Centers of PHM and DβH Atsushi Kunishita, Minoru Kubo, Hideki Sugimoto, Takashi Ogura, Kazunobu Sato, Takeji Takui,* and Shinobu Itoh* J. Am. Chem. Soc. 131 (8), 2788–2789 (2009).

銅タンパク質による酸素の活性化 伊東　忍 生産と技術, (2009).

2008

H2O2-Reactivity of Copper(II) Complexes Supported by TPA Ligands with 6-Phenyl Substituents Atsushi Kunishita, Minoru Kubo, Hirohito Ishimaru, Takashi Ogura, Hideki Sugimoto, and Shinobu Itoh* Inorg. Chem. 47 (24), 12032–12039 (2008).

Reaction of β−Diketiminate Copper(II) Complexes and Na2S2  Masayuki Inosako, Atsushi Kunishita, Chizu Shimokawa, Junji Teraoka, Minoru Kubo, Takashi Ogura, Hideki Sugimoto and Shinobu Itoh* Dalton Trans. (Article), 6250-6256 (2008).

Selenido-Bis(dithiolene) M(IV) Complexes (M = Mo and W) Potentially Related to the Nicotinic Acid Hydeosylase Reaction Center: Redox Aspects in Electrochemistry and Oxygen Atom Transfer from Me3NO to M(IV) Centers Hiroyuki Tano, Reiko Tajima, Hiroyuki Miyake, Shinobu Itoh, and Hideki Sugimoto* Inorg. Chem. (Communication), 47 (17), 7465–7467 (2008).

Reactions of Copper(II)–H2O2 Adducts Supported by Tridentate Bis(2-pyridylmethyl)amine Ligands: Sensitivity to Solvent and Variations in Ligand Substitution Atsushi Kunishita, Joseph D. Scanlon, Hirohito Ishimaru, Kaoru Honda, Takashi Ogura, Masatatsu Suzuki, Christopher J. Cramer,* and Shinobu Itoh* Inorg. Chem. (Article), 47 (18), 8222–8232 (2008).

A New Class of Sulfido/oxo(dithiolene)molybdenum(IV) Complexes Derived from Sulfido/oxo–bis(tetrasulfido)molybdenum(IV) Anions. Hideki Sugimoto,* Koichiro Suyama, Kunihisa Sugimoto, Hiroyuki Miyake, Isao Takahashi, Shun Hirota, and Shinobu Itoh Inorg. Chem. (Article), 47 (21), 10150–10157 (2008).

Colorimetric Response to Mercury-induced Abstraction of Triethylene Glycol Ligand from Gold Nanoparticle Surface Tasuku Hirayama, Masayasu Taki,* Yukiyasu Kashiwagi, Masami Nakamoto, Atsushi Kunishita, Shinobu Itoh and Yukio Yamamoto Dalton Trans, (Communication), 4705–4707 (2008).

Monooxygenase Activity of Octopus vulgaris Hemocyanin Kenji Suzuki, Chizu Shimokawa, Chiyuki Morioka, and Shinobu Itoh* Biochemistry (Article), 47 (27), 7108–7115 (2008).

Suggestion of an Organometallic Intermediate in an Intramolecular Dechlorination Reaction Involving Copper(I) and a ArCH2Cl Moiety Debabrata Maiti, Amy A. Narducci Sarjeant, Shinobu Itoh and Kenneth D. Karlin* J. Am. Chem. Soc. (Communication), 130 (17), 5644-5645 (2008).

Reactivity of Mononuclear Alkylperoxo Copper(II) Complex. O–O Bond Cleavage and C–H Bond Activation Atsushi Kunishita, Hirohito Ishimaru, Satoru Nakashima, Takashi Ogura, and Shinobu Itoh* J. Am. Chem. Soc. (Communication), 130 (13), 4244–4245 (2008).

2007

Reaction of Copper(II) Complexes and Na2S2. An Alternative Method for the Preparation of Disulfido-Dicopper(II) Complexes Masayuki Inosako, Chizu Shimokawa, Hideki Sugimoto, Nobuhiro Kihara, Toshikazu Takata, and Shinobu Itoh*
Chem. Lett. (Communication), 36 (11), 1306–1307 (2007).
 Aromatic Hydroxylation Reactivity of a Mononuclear Cu(II)-Alkylperoxo Complex
Atsushi Kunishita, Junji Teraoka, Joseph D. Scanlon, Takahiro Matsumoto, Masatatsu Suzuki, Christopher J. Cramer, and Shinobu Itoh*
J. Am. Chem. Soc. (Communication), 129 (23), 7248–7249 (2007). 
Catalytic Alkane Hydroxylation Reaction with Nickel(II) Complexes Supported by Di- and Triphenol Ligands
Takayuki Nagataki and Shinobu Itoh*
Chem. Lett. (Communication), 36 (6), 748–749 (2007). 
Model Studies of 6,7-Indolequinone Cofactors of Quinoprotein Amine Dehydrogenases Yoko Murakami, Noriyuki Yoshimoto, Nobutaka Fujieda, Kei Ohkubo, Tatsuhiko Hasegawa, Kenji Kano,* Shunichi Fukuzumi,* and Shinobu Itoh* J. Org. Chem. (Article), 72 (9), 3369–3380 (2007).

Monooxygenase Activity of Type-3 Copper Proteins Shinobu Itoh* and Shunichi Fukuzumi Acc. Chem. Res. (Account), 40 (7), 592–600 (2007).

Ligand effects on NiII-catalysed alkane-hydroxylation with m-CPBA Takayuki Nagataki, Kenta Ishii, Yoshimitsu Tachi, and Shinobu Itoh* Dalton Trans. (Article) (11), 1120–1128 (2007). (Selected Paper for Cover Picture)

In-situ Generation of Oxo-Sulfido Bis(dithiolene) Tungsten(VI) Complexes: Active Site Models for the Aldehyde Ferredoxin Oxidoreductase Family of Tungsten Enzymes.
Hideki Sugimoto,* Hiroyuki Tano, Reiko Tajima, Hiroyuki Miyake, Hiroshi Tsukube, Hiromi Ohi, and Shinobu Itoh
Inorg. Chem. (Communication), 46 (21), 8460–8462 (2007).
 Nucleophilic Substitution Accompanying Carbon-Carbon Bond Cleavage Assisted by a Nitro Group Yumi Nakaike, Noriko Taba, Shinobu Itoh, Yoshito Tobe, Nagatoshi Nishiwaki,* and Masahiro Ariga Bull. Chem. Soc. Jpn. 80 (12), 2413–2417 (2007). 
出会いあり、ハプニングありのICBIC（国際会議での武勇伝）
伊東　忍
化学（化学同人）, 62 (10), 56 (2007).

2006
Modeling the Mononuclear, Dinuclear, and Trinuclear Copper(I) Reaction Centers of Copper Proteins Using Pyridylalkylamine Ligands Connected to 1,3,5-Triethylbenzene Spacer Hiromi Ohi, Yoshimitsu Tachi, and Shinobu Itoh* Inorg. Chem. (Article), 45 (26), 10825–10835 (2006).

Ni(II)(TPA) as an efficient cataltst for alkane hydroxylation with m-CPBA Takayuki Nagataki, Yoshimitsu Tachi, and Shinobu Itoh* Chem. Commun. (Communication), (38), 4016–4018 (2006).
 Structure and O2-reactivity of copper(I) complexes supported by pyridylalkylamine ligands Shinobu Itoh* and Yoshimitsu Tachi Dalton Trans. (Perspective), (38) 4531–4538 (2006). (Selected Paper for Cover Picture)

Syntheses, Structures, and O2-Reactivities of Copper(I) Complexes of Bis(2-pyridylmethyl)amine and Bis(2-quinolylmethyl)amine Tridentate Ligands Atsushi Kunishita, Takao Osako, Yoshimitsu Tachi, Junji Teraoka,* and Shinobu Itoh* Bull. Chem. Soc. Jpn. (Article), 79 (11), 1729–1741 (2006). 
Significant Enhancement of Monooxygenase Activity of Oxygen Carrier Protein Hemocyanin by Urea Chiyuki Morioka, Yoshimitsu Tachi, Shinichiro Suzuki, and Shinobu Itoh* J. Am. Chem. Soc. (communication) 128 (21), 6788–6789 (2006).

Reversible Sulfurization-Desulfurization on the Tungsten-Bis(dithiolene) Complexes Hideki Sugimoto,* Reiko Tajima, Takeshi Sakurai, Hiromi Ohi, Hiroyuki Miyake, Shinobu Itoh, and Hiroshi Tsukube Angew. Chem. Int. Ed. (Communication), 45 (21), 3520–3522 (2006).

Intramolecular Arene Hydroxylation versus Intermolecular Olefin Epoxidation by (μ-η2:η2-Peroxo)dicopper(II) Complex Supported by Dinucleating Ligand Takahiro Matsumoto, Hideki Furutachi, Masashi Kobino, Masato Tomii, Shigenori Nagatomo, Takehiko Tosha, Takao Osako, Shuhei Fujinami, Shinobu Itoh, Teizo Kitagawa, and Masatatsu Suzuki* J. Am. Chem. Soc. (communication) 128 (12), 3874–3875 (2006).

A Functional Model for pMMO (Particulate Methane Monooxygenase). Oxygenation of Alkanes with H2O2 Catalysed by β-Diketiminatocopper(II) Complexes Chizu Shimokawa, Juniji Teraoka,* Yoshimitsu Tachi, and Shinobu Itoh* J. Inorg. Biochem. (Article), 100 (5, 6), 1118–1127 (2006).

Structural Characterization of Copper(I) Complexes Supported by β-Diketiminate Ligands with Different Substitution Patterns  Chizu Shimokawa, Yoshimitsu Tachi, Nagatoshi Nishiwaki, Masahiro Ariga, and Shinobu Itoh* Bull. Chem. Soc. Jpn. (Article), 79 (1), 118–125 (2006).

Mononuclear Copper Active-Oxygen Complexes Shinobu Itoh Curr. Opin. Chem. Biol. (Review) 10 (2), 115–122 (2006).

分子状酸素を活性化する銅タンパク質の化学 伊東　忍 化学と教育（日本化学会編）(解説) 54 (9), 482–485 (2006).

ブルース・エッセンシャル有機化学（第１版） 伊東　忍 教科書 (18章) (訳) (2006).

2005

Structure and photoluminescence property of two-dimensional coordination polymer complexes involving CuI6X6 (X = Cl, Br, I) hexagon prism cluster supported by a tripodal tripyridine ligand with 1,3,5-triethylbenzene spacer Hiromi Ohi, Yoshimitsu Tachi, Takashi Kunimoto and Shinobu Itoh* Dalton Trans. (Communication), (19) 3146–3147 (2005).

Kinetics and DFT Studies on the Reaction of Copper(II) Complexes and H2O2 Takao Osako, Shigenori Nagatomo, Teizo Kitagawa, Christopher J. Cramer,* and Shinobu Itoh* J. Biol. Inorg. Chem. (Article), 10 (5), 581–590 (2005).  The First β-Diketiminate Ag(I)-Complexes. Macrocyclic Dinuclear and Tetranuclear Ag(I)-Complexes and Linear Coordination Polymer Ag(I)-Complex
Chizu Shimokawa and Shinobu Itoh* Inorg. Chem. (Communication), 44 (9), 3010-3012 (2005).

Structure and Dioxygen-Reactivity of Copper(I) Complexes Supported by Bis(6-methylpyridin-2-yl-methyl)amine Tridentate Ligands Takao Osako, Shohei Terada, Takehiko Tosha, Shigenori Nagatomo, Hideki Furutachi, Shuhei Fujinami, Teizo Kitagawa, Masatatsu Suzuki and Shinobu Itoh* Dalton Trans. (Article), (21), 3514–3521 (2005).

Carbon-Halogen Bond Activation Mechanism by Copper(I) Complexes of (2-Pyridyl)alkylamine Ligands Takao Osako, Kenneth D. Karlin,* and Shinobu Itoh* Inorg. Chem. (Article), 44 (2), 410–415 (2005).

Synthesis, Characterization, and Catalytic Oxygenation Activity of Dinuclear Iron(III) Complex Supported by Binaphthol-Containing Chiral Ligand Takayuki Nagataki, Yoshimitsu Tachi, and Shinobu Itoh* J. Mol. Catal. A, Chemical (Article), 225 (1), 103-109 (2005).

Electron-transfer mechanism in radical-scavenging reactions by a vitamin E model in a protic medium Ikuo Nakanishi, Tomonori Kawashima, Kei Ohkubo, Hideko Kanazawa, Keiko Inami, Masataka Mochizuki, Kiyoshi Fukuhara, Haruhiro Okuda, Toshihiko Ozawa, Shinobu Itoh, Shunichi Fukuzumi and Nobuo Ikota Org. Biomol. Chem. (Article), 3, 626–629 (2005).  ピリジルアルキルアミン系配位子を用いた銅錯体の構造と反応性の精密制御—酵素活性中心モデルを中心に− 伊東　忍 有機合成化学協会誌（総合論文）, 63 (12), 1240–1252（2005）．

生物無機化学—金属元素と生物の関わりー
伊東　忍、他 錯体化学会選書、増田秀樹、福住俊一編、三共出版　(2005).

2004
C-S Bond Formation Reaction between Phenolate and Disulfide-bridged Dicopper(I) Complexes  Takao Osako, Yoshiki Ueno, Yoshimitsu Tachi, and Shinobu Itoh* Inorg. Chem. (Communication), 43 (21), 6516-6518 (2004).  Kinetic Evaluation of Catalase and Peroxygenase Activities of Tyrosinase Shin-ichi Yamazaki, Chiyuki Morioka, and Shinobu Itoh* Biochemistry (Article), 43 (36), 11546-11553 (2004).  Supramolecular and Coordination Polymer Complexes Supported by a Tripodal Tripyridine Ligand Containing a 1,3,5-Triethylbenzene Spacer  Hiromi Ohi, Yoshimitsu Tachi, and Shinobu Itoh* Inorg. Chem. (Communication), 43 (15), 4561-4563 (2004).  Dicopper-Dioxygen Complex Supported by Asymmetric Pentapyridine Dinucleating Ligand Yoshimitsu Tachi, Kazuki Aita, Shinichi Teramae, Fumito Tani, Yoshinori Naruta, Shunichi Fukuzumi, and Shinobu Itoh* Inorg. Chem. (Communication), 43 (15), 4558-4560 (2004).

A Model Compound of the Novel Organic Cofactor CTQ (Cysteine Tryptophylquinone) of Quinohemoprotein Amine Dehydrogenase Yoko Murakami, Yoshimitsu Tachi, and Shinobu Itoh* Eur. J. Org. Chem. (Article), 2004 (14), 3074-3079 (2004).

Model Complexes of the Active Site of Galactose Oxidase. Effects of the Metal Ion Binding Sites. Masayasu Taki, Haruna Hattori, Takao Osako, Shigenori Nagatomo, Motoo Shiro, Teizo Kitagawa, and Shinobu Itoh* Inorg. Chim. Acta (Article), 357 (11), 3369-3381 (2004).

Quantitative Evaluation of d-π Interaction in Copper(I) Complexes and Control of Copper(I)-Dioxygen Reactivity Takao Osako, Yoshimitsu Tachi, Matsumi Doe, Motoo Shiro, Kei Ohkubo, Shunichi Fukuzumi,* and Shinobu Itoh* Chem. Eur. J. (Article), 10 (1), 237-246 (2004).  Dinuclear Copper-Dioxygen Intermediates Supported by Polyamine Ligands Shinichi Teramae, Takao Osako, Shigenori Nagatomo, Teizo Kitagawa, Shunichi Fukuzumi, and Shinobu Itoh* J. Inorg. Biochem. (Article) 98 (5), 746-757 (2004).

EPR Study on Stable Magnesium Complexes of the Phenoxyl Radicals Derived from a Vitamin E Model and Its Deuterated Derivatives Ikuo Nakanishi, Shigenobu Matsumoto, Kei Ohkubo, Keiko Inami, Masataka Mochizuki, Toshihiko Ozawa, Shinobu Itoh, Shunichi Fukuzumi, and Nobuo Ikota Bull. Chem. Soc. Jpn. (Article), 77 (9), 1741-1744 (2004).

ブルース有機化学（第４版） 伊東　忍他 教科書（24、25章）（訳）(2004).  銅含有酸化酵素のモデル錯体—構造と機能— 伊東　忍 触媒（総説） 46 (4), 274-280 (2004). 
2003  Substituent Effects of b-Diketiminate Ligands on the Structure and Physicochemical Properties of The Copper(II) Complexes Chizu Shimokawa, Seiji Yokota, Yoshimitsu Tachi, Nagatoshi Nishiwaki, Masahiro Ariga, and Shinobu Itoh* Inorg. Chem. (Article), 42 (25), 8395-8405 (2003).

Kinetic Evaluation of Phenolase Activity of Tyrosinase using Simplified Catalytic Reaction System Shin-ichi Yamazaki and Shinobu Itoh* J. Am. Chem. Soc. (Communication), 125 (43), 13034–13035 (2003).

Structures and Redox Reactivities of Copper Complexes of (2-Pyridyl)alkylamine Ligands. Effects of the Alkyl Linker Chain Length Takao Osako, Yoshiki Ueno, Yoshimitsu Tachi, and Shinobu Itoh* Inorg. Chem. (Article), 42 (24), 8087–8097 (2003).

Oxidation Mechanism of Phenols by Dicopper-Dioxygen (Cu2/O2) Complexes  Takao Osako, Kei Ohkubo, Masayasu Taki, Yoshimitsu Tachi, Shunichi Fukuzumi,* and Shinobu Itoh* J. Am. Chem. Soc. (Article), 125 (36), 11027-11033 (2003).  Mechanism for Aerobic Oxidation of 3,5-Di-tert-butylcatechol to 2,3-Di-tert-butyl-o-benzoquinone Catalyzed by Di-m-hydroxo-dicopper(II) Complexes of Peralkylated Ethylenediamine Ligands Masahito Kodera,* Tomohisa Kawata, Koji Kano, Yoshimitsu Tachi, Shinobu Itoh, and Shosuke Kojo Bull. Chem. Soc. Jpn. (Article), 76 (10), 1957–1964 (2003).  Dicopper Enzymes (8.15) Shinobu Itoh Comprehensive Coordination Chemistry – II (Book), Elsevier, Amsterdam, Vol. 8, pp 369-393 (2003).

Oxygenation Mechanism of Phenols by Dinuclear Copper Monooxygenase Shinobu Itoh,* Shin-ichi Yamazaki, Hideki Kumei, Masayasu Taki, Takao Osako, and Shunichi Fukuzumi Biomolecular Chemistry (Proceeding Book of The first International Symposium on Biomolecular Chemistry, ISBC-2003), Maruzen Co., LTD., Tokyo, pp 150-155 (2003).  Dioxygen Activation by Copper Complexes Supported by 2-(2-Pyridyl)ethylamine Ligands. Mechanistic Insights into Copper Monooxygenases and Copper Oxidases Shinobu Itoh J. Inorg. Biochem. (Abstract of ICBIC-11), 96 (1), 20 (2003).  Oxidation Mechanism of Phenols by Dicopper-Dioxygen (Cu2/O2) Complexes. Takao Osako, Kei Okubo, Masayasu Taki, Yoshimitsu Tachi, Shunichi Fukuzumi, and Shinobu Itoh J. Inorg. Biochem. (Abstract of ICBIC-11), 96 (1), 207 (2003).  Synthesis and Characterization of Dicopper-Dioxygen Complex Supported by Novel Unsymmetrical Pentapyridine Ligand Yoshimitsu Tachi, Kazuki Aita, Shinichi Teramae, Fumito Tani, Yoshinori Naruta, Shunichi Fukuzumi, and Shinobu Itoh J. Inorg. Biochem. (Abstract of ICBIC-11), 96 (1), 236 (2003).

2002

Interconversion between Bis(m-thiolato)dicopper(II) and Disulfide-bridged Dicopper(I) Complexes Mediated by Chloride Ion Yoshiki. Ueno, Yoshimitsu Tachi, and Shinobu Itoh* J. Am. Chem. Soc. (Communication), 124 (42), 12428–12429 (2002).

Copper Chemistry of b-Diketiminate Ligands: Monomer/Dimer Equilibria and a New Class of Bis(μ-oxo)dicopper Compounds Douglas J. E. Spencer, Anne M. Reynolds, Patrick L. Holland, Brian A. Jazdzewski, Carole Toia, Seiji Yokota, Yoshimitsu Tachi, Shinobu Itoh,* and William B. Tolman* Inorg. Chem. (Article), 41 (24), 6307-6321 (2002).

Low-temperature Stopped-flow Studies on the Reaction of Cu(II) Complexes and H2O2. The First Detection of a Mononuclear Cu(II)-peroxo Intermediate. Takao Osako, Shigenori Nagatomo, Yoshimitsu Tachi, Teizo Kitagawa, and Shinobu Itoh* Angew. Chem. (Communication), 41 (22), 4325-4328 (2002).

Dioxygen Activation by Copper Complexes. Mechanistic Insights into Copper Monooxygenases and Copper Oxidases Shinobu Itoh* and Shunichi Fukuzumi Bull. Chem. Soc. Jpn. (Account, Selected Paper), 75 (10), 2081–2095 (2002).

Fine Tuning of Copper(I)-Dioxygen Reactivity by 2-(2-Pyridyl)ethylamine Bidentate Ligands Masayasu Taki, Shinichi Teramae, Shigenori Nagatomo, Yoshimitsu Tachi, Teizo Kitagawa, Shinobu Itoh,* and Shunichi Fukuzumi* J. Am. Chem. Soc. (Article), 124 (22), 6367–6377 (2002).

Oxidative Degradation of b-Diketiminate Ligand in Copper(II) and Zinc(II) Complexes Seiji Yokota, Yoshimitsu Tachi, and Shinobu Itoh* Inorg. Chem. (Communication), 41 (6), 1342–1344 (2002).

Oxo-transfer Reaction from A Bis(μ-oxo)dicopper(III) Complex Masayasu Taki, Shinobu Itoh*, and Shunichi Fukuzumi* J. Am. Chem. Soc. (Article), 124 (6), 998–1002 (2002).

Effects of Magnesium Ion on Kinetic Stability and Spin Distribution of Phenoxyl Radical Derived from a Vitamin E Analogue: Mechanistic Insight into Antioxidative Hydrogen-Transfer Reaction of Vitamin E Ikuo Nakanishi,* Kiyoshi Fukuhara,* Tomokazu Shimada, Kei Ohkubo, Yuko Iizuka, Keiko Inami, Masataka Mochizuki, Shiro Urano, Shinobu Itoh, Naoki Miyata, and Shunichi Fukuzumi* J. Chem. Soc., Parkin Trans. 2 (Article), (9), 1520 -1524 (2002).  Formation of Superoxide-Metal Ion Complexes and the Electron Transfer Catalysis Shunichi Fukuzumi,* Hideki Ohtsu, Kei Ohkubo, Shinobu Itoh, Hiroshi Imahori Coord. Chem. Rev. (Review Article), 266, 71–80 (2002).  2001  Modulation of Coordination Chemistry in Copper(I) Complexes Supported by Bis[2-(2-pyridyl)ethyl]amine-Based Tridentate Ligands Takao Osako, Yoshimitsu Tachi, Masayasu Taki, Shunichi Fukuzumi, and Shinobu Itoh Inorg. Chem. (Article), 40 (26), 6604-6609 (2001).  Formation, Characterization, and Reactivity of Bis(μ-oxo)dinickel(III) Complexes Supported by A Series of Bis[2-(2-pyridyl)ethyl]amine Ligands Shinobu Itoh, Hideki Bandoh, Motonobu Nakagawa, Shigenori Nagatomo, Teizo Kitagawa, Kenneth D. Karlin, and Shunichi Fukuzumi J. Am. Chem. Soc. (Article), 123 (45), 11168-11178 (2001).

A New β-Diketiminate Ligand Carrying a Functional Group on the Carbon Framework. Synthesis and Characterization of a Linear Polymeric Copper(I) Complex Seiji Yokota, Yoshimitsu Tachi, Nagatoshi Nishiwaki, Masahiro Ariga, and Shinobu Itoh Inorg. Chem. (Communication), 40 (21), 5316-5317 (2001).   Oxygenation of Phenols to Catechols by a μ-η2:η2-Peroxo)dicopper (II) Complex. Mechanistic Insight into the Phenolase Activity of Tyrosinase Shinobu Itoh, Hideyuki Kumei, Masayasu Taki, Shigenori Nagatomo, Teizo Kitagawa, and Shunichi Fukuzumi J. Am. Chem. Soc. (Communication), 123 (27),6708-6709 (2001).

C-H Bond Activation of External Substrates with a Bis(m-oxo)dicopper(III) Complex Masayasu Taki, Shinobu Itoh, and Shunichi Fukuzumi J. Am. Chem. Soc. (Communication), 123 (25), 6203-6204 (2001).

Fine Tuning of the Interaction between the Copper(I) and Disulfide Bond. Formation of a Bis(m-thiolato)dicopper(II) Complex by Reductive Cleavage of the Disulfide Bond with Copper(I) Shinobu Itoh, Motonobu Nakagawa, and Shunichi Fukuzumi J. Am. Chem. Soc. (Communication), 123 (17), 4087-4088 (2001).

Effects of Metal Ions on Physicochemical Properties and Redox Reactivity of Phenolates and Phenoxyl Radicals. Mechanistic Insight into Hydrogen Atom Abstraction by Phenoxyl Radical-Metal Complexes Shinobu Itoh, Hideyuki Kumei, Shigenori Nagatomo, Teizo Kitagawa, and Shunichi Fukuzumi J. Am. Chem. Soc. (Article), 123 (10), 2165-2175 (2001).

Catalytic Control of Redox Reactivities of Coenzyme Analogs by Metal Ions Shunichi Fukuzumi and Shinobu Itoh Antioxidants and Redox Signaling (Review Article), 3 (5), 807-824 (2001).

Oxidative Modification of Tryptophan-43 in the Heme Vicinity of the F43W/H64L Myoglobin Mutant Isao Hara, Takahumi Ueno, Shin-ichi Ozaki, Shinobu Itoh, Ken-ichi Lee, Norikazu Ueyama, and Yoshihito Watanabe J. Biol. Chem. (Rapid Communication), 276 (39), 36067-36070 (2001).

Characterization of Imidazolate-Bridged Dinuclear and Mononuclear Hydroperoxo Complexes Hideki Ohtsu, Shinobu Itoh, Shigenori Nagatomo, Teizo Kitagawa, Seiji Ogo, Yoshihito Watanabe, and Shunichi Fukuzumi Inorg. Chem. (Article), 40 (13), 3200-3207 (2001).

2000

Effects of Metal Ions on the Electronic, Redox, and Catalytic Properties of Cofactor TTQ of Quinoprotein Amine Dehydrogenases Shinobu Itoh, Makoto Taniguchi, Naoki Takada, Shigenori Nagatomo, Teizo Kitagawa, and Shunichi Fukuzumi J. Am. Chem. Soc., 122 (48), 12087-12097 (2000).   Photochemical Reactions of Coenzyme PQQ (Pyrroloquinolinequinone) and Analogs with Benzyl Alcohol Derivatives via Photoinduced Electron Transfer  Shunichi Fukuzumi, Shinobu Itoh, Takashi Komori, Tomoyoshi Suenobu, Akito Ishida, Mamoru Fujitsuka, and Osamu Ito J. Am. Chem. Soc., 122 (35), 8435-8443 (2000).  Model Complexes of the Active Form of Galactose Oxidase. Physicochemical Properties and Reactivity of Cu(II)- and Zn(II)-Phenoxyl Radical Complexes Shinobu Itoh, Masayasu Taki, Hideyuki Kumei, Shigehisa Takayama, Shigenori Nagatomo, Teizo Kitagawa, Norio Sakurada, Ryuichi Arakawa, and Shunichi Fukuzumi Inorg. Chem., 39 (16), 3708-3711 (2000).  Aliphatic Hydroxylation by a Bis(μ-oxo)dicopper(III) Complex Shinobu Itoh, Masayasu Taki, Hajime Nakao, Patrick L. Holland, William B. Tolman, Lawrence Que, Jr., and Shunichi Fukuzumi Angew. Chem., 112 (2), 409-411 (2000); Angew. Chem., Int. Ed., 39 (2), 398-400 (2000).  Catalytic Effect of Monovalent Cations on the Amine-Oxidation by Cofactor TTQ of Quinoprotein Amine Dehydrogenases Shinobu Itoh, Masato Taniguchi, and Shunichi Fukuzumi Chem. Commun., (5), 329-330 (2000).  Active Site Models for Galactose Oxidase and Related Enzymes Shinobu Itoh, Masayasu Taki, and Shunichi Fukuzumi Coord. Chem. Rev., 198, 3-20 (2000).  Hydrogen Atom Abstraction by Cu(II)- and Zn(II)-Phenoxyl Radical Complexes, Model Complexes of Active Form of Galactose Oxidase Masayasu Taki, Hideyuki Kumei, Shinobu Itoh, and Shunichi Fukuzumi J. Inorg. Biochem. (Special Issue of ICBIC-9), 78 (1), 1-5 (2000).  Active Site Model for Galactose Oxidase Containing Two Different Phenol Groups Masayasu Taki, Hideyuki Kumei, Shigenori Nagatomo, Teizo Kitagawa, Shinobu Itoh, and Shunichi Fukuzumi Inorg, Chim. Acta (Special Volume 300), 300-302, 622-632 (2000).  Development of the Active Site Model for Calcium-Containing Quinoprotein Alcohol Dehydrogenases Shinobu Itoh, Hirokatsu Kawakami, Shunichi Fukuzumi J. Mol. Catal. B: Enzymatic (Memorial Issue for Prof. J. A. Duine's Retirement), 8, 85-94 (2000).  Reaction of Cu(I) Complexes Bearing a Phenol Group in the Ligand with O2 Shinobu Itoh, Yasuji Hashimoto, and Shunichi Fukuzumi Appl. Catal., A: General (Memorial Issue for the Retirement of Prof. Y. Moro-oka's), 194-195, 453-461 (2000)

Redox Functions of Novel o-Quinone Coenzymes Shinobu Itoh Electrochemistry, 68 (10), 807-811 (2000).  Resonance Raman Spectroscopy as a Probe of the Bis(m-oxo)dicopper Core P. L. Holland, C. J. Cramer, E. C. Wilkinson, S. Mahapatra, K. R. Rodgers, Shinobu Itoh, M. Taki, S. Fukuzumi, L. Que, Jr., and W. B. Tolman J. Am. Chem. Soc., 122 (5), 792-802 (2000).  Synthesis and Characterization of Imidazolate-Bridged Dinuclear Complexes as Active Site Models of Cu/Zn-SOD Hideki Ohtsu, Yuichi Shimazaki, Osamu Yamauchi, Wasuke Mori, Shinobu Itoh, and Shinichi Fukuzumi J. Am. Chem. Soc., 122, 5733-5741 (2000).  Characterization of Imidazolate-Bridged Cu(II)-Zn(II) Heterodinuclear and Cu(II)-Cu(II) Homodinuclear Hydroperoxo Complexes as Reaction Intermediate Models of Cu, Zn-SOD  Hideki Ohtsu, Shinobu Itoh, Shigenori Nagatomo, Teizo Kitagawa, Seigi Ogo, Yoshihito Watanabe, and Shunichi Fukuzumi Chem. Commun., 1051-1052 (2000).  1999  Aliphatic Hydroxylation by a Bis(m-oxo)dinickel(III) Complex Shinobu Itoh, Hideki Bandoh, Shigenori Nagatomo, Teizo Kitagawa, and Shunichi Fukuzumi J. Am. Chem. Soc., 121 (38), 8945-8946 (1999).  Oxidation of Benzyl Alcohol with Cu(II) and Zn(II) Complexes of Phenoxyl Radical as a Model Reaction of Galactose Oxidase Shinobu Itoh, Masayasu Taki, Shigehisa Takayama, Shigenori Nagatomo, Teizo Kitagawa, Norio Sakurada, Ryuichi Arakawa, and Shunichi Fukuzumi Angew. Chem., 111 (18), 2944-2946 (1999); Angew. Chem., Int. Ed., 38 (18), 2774-2776 (1999).  ESR Spectra of Superoxide Anion-Scandium Complexes Detectable in Fluid Solution Shunichi Fukuzumi, Matthias Patz, Tomoyoshi Suenobu, Yoshihiro Kuwahara, and Shinobu Itoh J. Am. Chem. Soc., 121 (7), 1605-1606 (1999).  Electron Transfer Properties of Active Aldehydes of Thiamin Coenzyme Models and Mechanism of Formation of the Reactive Intermediates Ikuo Nakanishi, Shinobu Itoh, and Shunichi Fukuzumi Chem. Eur. J., 5 (10), 2810-2818 (1999).  Catalysis of Photoinduced Electron Transfer Reactions, Shunichi Fukuzumi and Shinobu Itoh Advances in Photochemistry, Vol. 25, eds. by D. C. Neckers, D. H. Volman, and G. von Bunau, Wiley, New York, 107-172 (1999).  1998  Mechanistic Studies of Aliphatic Ligand Hydroxylation of a Copper Complex by Dioxygen: A Model Reaction for Copper Monooxygenases Shinobu Itoh, Hajime Nakao, Lisa M. Berreau, Toshihiko Kondo, Mitsuo Komatsu, and Shunichi Fukuzumi J. Am. Chem. Soc., 120 (12), 2890-2899 (1998).  Model Studies of Calcium-containing Quinoproteins Alcohol Dehydrogenaes. Catalytic Role of Ca2+ for the Oxidation of Alcohols by Coenzyme PQQ (4,5-dihydro-4,5-dioxo-1H-pyrrolo- [2,3-f]quinoline-2,7,9-tricarboxylic acid) Shinobu Itoh, Hirokatsu Kawakami, and Shunichi Fukuzumi Biochemistry, 37 (18), 6562-6571 (1998).  Electrochemical Behavior and Characterization of Semiquinone Radical Anion Species of Coenzyme PQQ in Aprotic Organic Media Shinobu Itoh, Hirokatsu Kawakami, and Shunichi Fukuzumi J. Am. Chem. Soc., 120 (29), 7271-7277 (1998).  Direct Observation of Radical Intermediates while Investigating the Redox Behavior of Thiamin Coenzyme Models Ikuo Nakanishi, Shinobu Itoh, Tomoyoshi Suenobu, and Shunichi Fukuzumi Angew. Chem., 110 (7), 1040-1042; Angew. Chem., Int. Ed., 37 (7), 992-994 (1998).  Formation of Radical Anion in the Reaction of p-Benzoquinone and C60 with Alkoxide Ions Shunichi Fukuzumi, Ikuo Nakanishi, Junichi Maruta, Tomohiro Yorisue, Tomoyoshi Suenobu, Shinobu Itoh, Ryuichi Arakawa, and Karl M. Kadish J. Am. Chem. Soc., 120 (27), 6673-6680 (1998).  Selective One-Electron and Two-Electron Reduction of C60 with NADH and NAD Dimer Analogues via Photoinduced Electron Transfer Shunichi Fukuzumi, Tomoyoshi Suenobu, Matthias Patz, Takeomi Hirasaka, Shinobu Itoh, Mamoru Fujitsuka, and Osamu Ito J. Am. Chem. Soc., 120 (32), 8060-8068 (1998).  1997  Modeling of the Chemistry of Quinoprotein Methanol Dehydrogenase. Oxidation of Methanol by Calcium Complex of Coenzyme PQQ via Addition-Elimination Mechanism Shinobu Itoh, Hirokatsu Kawakami, and Shunichi Fukuzumi J. Am. Chem. Soc., 119 (2), 439-440 (1997).  Catalysis by Calcium Ion of the Reoxidation of Reduced PQQ by Molecular Oxygen Shinobu Itoh, Hirokatsu Kawakami, and Shunichi Fukuzumi Chem. Commun., (1), 29-30 (1997).  Active Site Models for Galactose Oxidase. Electronic Effect of the Thioether Group in the Novel Organic Cofactor Shinobu Itoh, Shigehisa Takayama, Akihiro Furuta, Mitsuo Komatsu, Akito Ishida, Setsuo Takamuku, Ryuichi Arakawa, Shunichi Fukuzumi Inorg. Chem., 36 (7), 1407-1416 (1997).  Synthesis, Physicochemical Properties, and Amine-Oxidation Reaction of Indolequinone Derivatives as Model Compounds of Novel Organic Cofactor TTQ of Amine Dehydrogenases Shinobu Itoh, Naoki Takada, Takeya Ando, Shigenobu Haranou, Xin Huang, Yasushi Uenoyama, Yoshiki Ohshiro, Mitsuo Komatsu, and Shunichi Fukuzumi J. Org. Chem., 62 (17), 5898-5907 (1997).  Cleavage Mode of Benzyltributylstannane Radical Cations Produced in Photoinduced Electron Transfer Shunichi Fukuzumi, Kiyomi Yasui, and Shinobu Itoh Chem. Lett., (2), 161-162 (1997).  Redox Behavior of Active Aldehyde Derived from Thiamin Coenzyme Analogs Ikuo Nakanishi, Shinobu Itoh, Tomoyoshi Suenobu, Hiroo Inoue, and Shunichi Fukuzumi Chem. Lett., (8), 707-708 (1997).  Electron Transfer Properties of Active Aldehydes Derived from Thiamin Coenzyme Analogues Ikuo Nakanishi, Shinobu Itoh, Tomoyoshi Suenobu, and Shunichi Fukuzumi Chem. Commun., (19), 1927-1928 (1997).  Metal Ion-Complexes of alpha,beta-Unsaturated Ketones Acting as Actual Reactive Species in Michael Addition of Ketene Silyl Acetal Shunichi Fukuzumi,Toshihiko Okamoto, Kiyomi Yasui, Tomoyoshi Suenobu, Shinobu Itoh and Junzo Otera Chem. Lett., (), 667-668 (1997).  Mechanistic Studies of Aliphatic Ligand Hydroxylation of a Copper Complex by Dioxygen: A Model Reaction for Copper Monooxygenases Shinobu Itoh, Hajime Nakao, and Shunichi Fukuzumi J. Inorg. Biochem., 67 (1-4), 65 (1997).  Redox Catalysis of Novel Heterocyclic o-Quinone Coenzymes Shinobu Itoh, Hirokatsu Kawakami, and Shunichi Fukuzumi Novel Trends in Electroorganic Synthesis, ed. by Shigeru Torii, pp.15-18 (1997).  1996  The Photochemical Oxidation of Benzyl Alcohols by the Triplet Excited State of Coenzyme Pyrroloquinonlinequinone. Shinobu Ioth, Takashi Komori, Yutaka Chiba, Akito Ishida, Setsuo Takamuku, and Shunichi Fukuzumi Chem. Commun., (4), 465-466 (1996).  Addition-Cyclization Reaction of Nitroalkane Anions with o-Quinone Derivatives via Electron Transfer in the Charge-transfer Complexes Shinobu Itoh, Junichi Maruta, and Shunichi Fukuzumi J. Chem. Soc., Perkin Trans 2, (7), 1429-1433 (1996).  Electrostatic Environment of the Tryptophylquinone Cofactor in Methylamine Dehydrogenase. Evidence from Resonance Raman Spectroscopy of Model Compounds Pierre. Moenne-Loccoz, Nobuhumi Nakamura, Shinobu Itoh, Shunichi Fukuzumi, Antonius C. F. Gorren, Johannis A. Duine, and Joann Sanders-Loehr Biochemistry, 35 (15), 4713-4720 (1996).  Model Studies of TTQ-Containing Amine Dehydrogenases  Shinobu Itoh, Naoki Takada, Shigenobu Haranou, Takeya Ando, Mitsuo Komatsu, Yoshiki Ohshiro, and Shunichi Fukuzumi J. Org. Chem., 61(25), 8967-8974 (1996).  Mechanism of Electron Transfer Oxidation of 4-Substituted 1-Benzyl-1,4-dihydronicotinamides Naoki Takada, Shinobu Itoh, and Shunichi Fukuzumi Chem. Lett. (12), 1103-1104 (1996).  インタ−ネットで化学する（１）−パソコン通信からインタ−ネットへ− 伊東　忍 化学と工業、49 (6), 777 (1996).  酸化と還元 伊東　忍 化学、51 (7), 416-417 (1996).  1995  A Model Compound of Novel Cofactor Tryptophan Tryptophylquinone of Bacterial Methylamine Dehydrogenases. Synthesis and Physicochemical Properties Shinobu Itoh, Masaki Ogino, Shigenobu Haranou, Tadashi Terasaka, Takeya Ando, Mitsuo Komatsu, Yoshiki Ohshiro, Shunichi Fukuzumi, Kenji Kano, Kazuyoshi Takagi, and Tokuji Ikeda J. Am. Chem. Soc., 117 (5), 1485-1493 (1995).  Functional Model of Dopamine b-Hydroxylase. Quantitative Ligand Hydroxylation at the Benzylic Position of a Copper Complex by Dioxygen Shinobu Itoh, Toshihiko Kondo, Mitsuo Komatsu, Yoshiki Ohshiro, Chunmin Li, Nobuko Kanehisa, Yasushi Kai, and Shunichi Fukuzumi J. Am. Chem. Soc., 117 (16), 4714-4715 (1995).  An Active Site Model for Calsium-Contaoning Quinoproteins Shinobu Itoh, Xin Huang, Mitsuo Komatsu, Yoshiki Ohshiro, and Shunichi Fukuzumi J. Chem. Soc., Chem. Commun., 2077-2078 (1995).  The Chemistry of Heterocyclic o-Quinone Cofactors Shinobu Itoh and Yoshiki Ohshiro Natural Product Reports (The Royal Society of Chemistry, UK), 12 (1), 45-53 (1995).  Model Studies of Cofactor TTQ Shinobu Itoh and Yoshiki Ohshiro Methods in Enzymology, J. P. Klinman Ed., Academic Press, Inc., San Diego, pp 164-176 (1995).  1994  Modeling of Quinoprotein Functions Yoshiki Ohshiro and Shinobu Itoh Pure Appl. Chem., 66 (4) 753-758 (1994).  Model Studies Directed toward the Action of Quinoprotein Methanol Dehydrogenase Shinobu Itoh "Biochemistry of Vitamin B6 & PQQ", eds. by G. Mariano, G. Sannia, and F. Bossa, Birkhauser Verlag Bassel/Switzerland, pp 297-301 (1994).  補酵素の新しい仲間たち−酵素三元｡合体の結晶構造解析− 伊東　忍 化学、49 (10), 736 (1994).  1993  C-4 and C-5 Adducts of Cofactor PQQ (Pyrroloquinolinequinone). Model Studies Directed toward the Action of Quinoprotein Methanol Dehydrogenase Shinobu Itoh, Masaki Ogino, Yoshifumi Fukui, Hiroshi Murao, Mitsuo Komatsu, Yoshiki Ohshiro, Tsuyoshi Inoue, Yasushi Kai, and Nobutami Kasai J. Am. Chem. Soc., 115 (22), 9960-9967 (1993).  Physicochemical Properties of 2-Methylthio-4-methylphenol, a Model Compound of the Novel Cofactor of Galactose Oxidase Shinobu Itoh, Keisuke Hirano, Akihiro Furuta, Mitsuo Komatsu, Yoshiki Ohshiro, Akito Ishida, Setsuo Takamuku, Takamitsu Kohzuma, Nobufumi Nakamuka, and Sninnichiro Suzuki Chem. Lett., (12), 2099-2102 (1993).  Multinuclear NMR and Ab Initio MO Studies of 7-Methyl-7H-Pyrrolo[2,3-b]pyridine and Related Compounds Satoshi Minakata, Shinobu Itoh, Komatsu Mitsuo, Yoshiki Ohshiro, and Yasunori Yokomichi J. Phys. Org. Chem., 6 (1), 139-144 (1993).  Ring Enlargement of Diaziridinone with 2-Substituted Pyrrole Leading to Bicyclic Triazine and Its Transformation to Novel Mesomeric Betaine Mitsuo Komatsu, Mitsuharu Kobayashi, Shinobu Itoh, and Yoshiki Ohshiro J. Org. Chem., 58 (24), 6620-6624 (1993).  新規な複素環オルトキノン系補酵素の化学的機能と応用 伊東　忍 有機合成化学協会 (総合論文), 51 (12), 1154-1163 (1993).  1992  Synthesis and Characterization of the Model Compound of Active Site Cofactor, TTQ (Tryptophan Tryptophylquinone), of Bacterial Methylamine Dehydrogenase Shinobu Itoh, Masaki Ogino, Mitsuo Komatsu, and Yoshiki Ohshiro J. Am. Chem. Soc., 114 (18), 7294-7295 (1992).  Synthesis and Characterization of the 6-Deaza Derivative of Coenzyme PQQ, Methyl 4,5-Dihydro-4,5-dioxobenz[g]indole-2-carboxylate Shinobu Itoh, Yoshifumi Fukui, Masaki Ogino, Shigenobu Haranou, Mitsuo Komatsu, and Yoshiki Ohshiro J. Org. Chem., 57 (10), 2788-2793 (1992).  Synthesis and Characterization of Dimethyl 9,10-Dihydro-9,10-dioxobenzoquinoline- 2,4-dicarboxylate. Effect of the Pyrrole Nucleus on the Reactivity of Coenzyme PQQ Shinobu Itoh, Yoshifumi Fukui, Shigenobu Haranou, Masaki Ogino, Mitsuo Komatsu, and Yoshiki Ohshiro J. Org. Chem., 57 (16), 4452-4457 (1992).  Reaction of Coenzyme PQQ with Amino Acids. Oxidative Decarboxylation, Oxidative Dealdolation (Cα-Cβ Fission) and Oxazolopyrroloquinoline (OPQ) Formation Shinobu Itoh, Minae Mure, Atsuko Suzuki, Hiroshi Murao, and Yoshiki Ohshiro J. Chem. Soc., Perkin Trans 2, (8), 1245-1251 (1992).  Heterocyclic o-Quinones. Mediator for Electrochemical Oxidation of NADH Shinobu Itoh, Hajime Fukushima, Mitsuo Komatsu, and Yoshiki Ohshiro Chem. Lett., (8), 1583-1586 (1992).  Efficient NAd+-recycling System for ADH-catalysed Oxidation in Organic Media Shinobu Itoh, Tadashi Terasaka, Morio Matsumiya, Mitsuo Komatsu, and Yoshiki Ohshiro J. Chem. Soc., Perkin Trans 1 (Perkin Communication), (24), 3251-3252 (1992).  Ring Enlargement of Diaziridinone: Reactions with Bifunctionalized Carboanions Leading to Functionalized Pyrazolines or Novel Spiroheterocycles Mitsuo Komatsu, Yohko Kajihara, Mitsuharu Kobayashi, Shinobu Itoh, and Yoshiki Ohshiro J. Org. Chem., 57 (26), 3759-3761 (1992).  Functionalization of 1H-Pyrrolo[2,3-b]pyridine Satoshi Minakata, Shinobu Itoh, Mitsuo Komatsu, and Yoshiki Ohshiro Bull. Chem. Soc. Jpn., 65 (11), 2992-2997 (1992).  補酵素ＰＱＱの化学的機能 伊東　忍、大城芳樹 日本農|化学会誌、66 (11), 1649-1652 (1992).  The Chemistry of PQQ and Related Compounds Yoshiki Ohshiro and Shinobu Itoh "Principles and Applications of Quinoproteins" Victor L. Davidson Ed., Marcel Dekker Inc, New York, 309-329 (1992).  1991  Reaction of the Trimethyl Ester of Coenzyme PQQ (PQQTME) and Amines in Organic Media. Products and Mechanism Shinobu Itoh, Minae Mure, Masaki Ogino, and Yoshiki Ohshiro J. Org. Chem., 56 (24), 6857-6865 (1991).  Mechanism of Amine Oxidation by Coenzyme PQQ Yoshiki Ohshiro and Shinobu Itoh Bioorg. Chem., 19 (2), 169-189 (1991).  Chemical Behavior of Coenzyme PQQ toward Amino Acids Yoshiki Ohshiro and Shinobu Itoh Enzymes Dependent on Pyridoxal Phosphate and Other Carbonyl Compounds as Cofactors, ed. by T. Fukui, H. Kagamiyama, K. Soda, and H. Wada, Pergamon Press, Oxford, pp 457-464 (1991).  1990  The Reaction of Coenzyme PQQ with Hydrazines Minae Mure, Kazumi Nii, Teruhisa Inoue, Shinou Itoh, and Yoshiki Ohshiro J. Chem. Soc., Perkin 2, (2), 315-320 (1990).  Chemical Behavior of Coenzyme PQQ toward Aminoguanidine: Redox Reaction and Adduct Formation Minae Mure, Kazumi Nii, Shinobu Itoh, and Yoshiki Ohshiro Bull. Chem. Soc. Jpn, 63 (2), 417-420 (1990).  Regioselective Transformation of the Functional Groups of Coenzyme PQQ Shinobu Itoh, Teruhisa Inoue, Yoshifumi Fukui, Xin Huang, Mitsuo Komatsu, and Yoshiki Ohshiro Chem. Lett., (9), 1675-1678 (1990).  Efficient NAd+-Regeneration System with Heterocyclic o-Quinones and Molecular Oxygen Catalyzed by Diaphorase Shinobu Itoh, Naruyoshi Mita, and Yoshiki Ohshiro Chem. Lett., (10), 1949-1952 (1990).  Oxidative Cα-Cβ Fission (Dealdolation) of α-Hydroxy Amino Acids by Coenzyme PQQ Minae Mure, Atsuko Suzuki, Shinobu Itoh, and Yoshiki Ohshiro J. Chem. Soc., Chem. Commun., (22), 1608-1611 (1990).  1989  Efficient NAD+-regeneration System with Heteroaromatic o-Quinones and Molecular Oxygen Shinobu Itoh, Masashi Kinugawa, Naruyoshi Mita, and Yoshiki Ohshiro J. Chem. Soc., Chem. Commun., (11), 694-695 (1989).  Chemical Behavior of Coenzyme PQQ toward Diamines Minae Mure, Shinobu Itoh, and Yoshiki Ohshiro Chem. Lett., (8), 1491-1494 (1989).  Preparation and Characterization of Iminoquinone and Aminophenol Derivatives of Coenzyme PQQ Minae Mure, Shinobu Itoh, and Yoshiki Ohshiro Tetrahedron Lett., 30 (49), 6875- 6878 (1989).  新規補酵素ＰＱＱの化学的機能 大城芳樹、伊東　忍 有機合成化学協会誌 (総合論文), 47 (9), 855-867 (1989).  The Chemistry and Biomimetics of PQQ Yoshiki Ohshiro and Shinobu Itoh PQQ and Quinoproteins, ed. by J. A. Jongejan and J. A. Duine, Kluwer Academic Publishers, London, pp 195-204 (1989).  Reaction of PQQ and Its Analogues with NADH: Application to the HLADH-catalyzed Oxidation of Alcohols Shinobu Itoh, Masashi Kinugawa, and Yoshiki Ohshiro PQQ and Quinoproteins, ed. by J. A. Jongejan and J. A. Duine, Kluwer Academic Publishers, London, pp 236-238 (1989).  Chemical Behavior of Coenzyme PQQ toward Amine Homologs Yoshiki Ohshiro, Minae Mure, Kazumi Nii, and Shinobu Itoh PQQ and Quinoproteins, ed. by J. A. Jongejan and J. A. Duine, Kluwer Academic Publishers, London, pp 239-241 (1989).  1988  Preparation and Characterization of Ternary Copper (II) Complexes Containing Coenzyme PQQ and Bipyridine or Terpyridine Shinnichiro Suzuki, Takesi Sakurai, Shinobu Itoh, and Yoshiki Ohshiro Inorg. Chem., 27 (4), 591-592 (1988).  Characterization of Ternary Copper (II) Complexes Containing Reduced PQQ (PQQH2) and Bipyridine or Terpyridine Shinnichiro Suzuki, Takeshi Sakurai, Shinobu Itoh, and Yoshiki Ohshiro Chem. Lett., (5), 777-780 (1988).  Characterization of Ternary Copper (II) Complexes Containing 1-Methyl Derivative of PQQ  Shinnichiro Suzuki, Takeshi Sakurai, Shinobu Itoh, and Yoshiki Ohshiro J. Chem. Soc. Jpn., (4), 421-424 (1988).  1987  Kinetic Studies on the Oxidation of Thiols by Coenzyme PQQ Shinobu Itoh, Nobuyuki Kato, Minae Mure, and Yoshiki Ohshiro Bull. Chem. Soc. Jpn. 60 (1), 420-422 (1987).  Novel Addition of Nitroalkanes to o-Quinones Shinobu Itoh, Kazumi Nii, Minae Mure, and Yoshiki Ohshiro Tetrahedron Lett., 28 (34), 3975-3978 (1987).  Syntheses of Pyrroloquinoline Quinone Derivatives: Model Compounds of a Novel Coenzyme PQQ (Methoxatin) Shinobu Itoh, Jin-ichiro Kato, Teruhisa Inoue, Yutaka Kitamura, Mitsuo Komatsu, and Yoshiki Ohshiro Synthesis, (12), 1067-1071 (1987).  Oxidation of D-Glucose by Coenzyme PQQ: 1,2-Enediolates as Substrates for PQQ Oxidation Shinobu Itoh, Minae Mure, and Yoshiki Ohshiro J. Chem. Soc., Chem. Commun., (7), 1580-1581 (1987).  Reaction of 2,3-Diphenylthiirene 1-Oxide with Nucleophiles Shinobu Itoh, Mitsuo Komatsu, and Yoshiki Ohshiro Nippon Kagaku Kaishi, (7), 1393-1396 (1987).  Oxidative Deamination of Aliphatic Amines by Coenzyme PQQ in the Micellar System Shinobu Itoh, Minae Mure, and Yoshiki Ohshiro J. Jpn. Oil Chem. Soc., 36 (11), 882-883 (1987).  1986  Effects of Surfactants on the Oxidative Deamination of Amines by Coenzyme PQQ Shinobu Itoh, Yutaka Kitamura, and Yoshiki Ohshiro J. Jpn. Oil Chem. Soc., 35 (2), 91-96 (1986).  Hydrolysis of Ester Groups of Coenzyme PQQ-trimethyl Ester (PQQTME) Shinobu Itoh and Yoshiki Ohshiro Chem. Exp., 1 (5), 315-318 (1986).  Kinetics and Mechanism of the Oxidative Deamination of Amines by Coenzyme PQQ Shinobu Itoh, Yutaka Kitamura, Yoshiki Ohshiro, and Toshio Agawa Bull. Chem. Soc. Jpn., 59 (6), 1907-1910 (1986).  Reaction of Reduced PQQ (PQQH2) and Molecular Oxygen Shinobu Itoh, Yoshiki Ohshiro, and Toshio Agawa Bull. Chem. Soc. Jpn., 59 (6), 1911-1914 (1986).  The 9-Carboxy Group of Pyrroloquinoline Quinone, a Novel Prosthetic Group, is Essential in the Formation of Holoenzyme of D-Glucose Dehydrogenase Emiko Shinagawa, Kazunobu Matsushita, Masatsugu Nonobe, Osao Adachi, Minoru Ameyama, Yoshiki Ohshiro, Shinobu Itoh, and Yutaka Kitamura Biochem. Biophys. Res. Commun., 139 (3), 1279-1284 (1986).  新しい補酵素ＰＱＱ−有機化学的側面から− 大城芳樹、伊東　忍 化学、41 (8), 495-500 (1986).  新しい補酵素ＰＱＱによる酸化還元反応 大城芳樹、伊東　忍 生産と技術, 31-33 (1986).  1985  Catalytic Oxidation of Thiols by Coenzyme PQQ Shinobu Itoh, Nobuyuki Kato, Yoshiki Ohshiro, and Toshio Agawa Chem. Lett., (1), 135-136 (1985).  Biomimetic Oxidation of Alcohols by Coenzyme PQQ-Trimethyl Ester Shinobu Itoh, Minae Mure, Yoshiki Ohshiro, and Toshio Agawa  Tetrahedron Lett., 26 (35), 4225-4228 (1985).  1984  Oxidative Decarboxylation of α-Amino Acids with Coenzyme PQQ Shinobu Itoh, Nobuyuki Kato, Yoshiki Ohshiro, and Toshio Agawa Tetrahedron Lett., 25 (42), 4753-4756 (1984).  1983  Micelle Enhanced Oxidation of Amines by Coenzyme PQQ Yoshiki Ohshiro, Shinobu Itoh, Ken Kurokawa, Jin-ichiro Kato, Toshikazu Hirao, and Toshio Agawa Tetrahedron Lett., 24 (33), 3465-3468 (1983).

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